Inside air can be more polluted than outside air. Engineering the problems will not really solve anything. Too often it is all about using mechanical ventilators which pose their own health hazards.
Cement has mercury in it and is a major modern building material.
Mold is a major issue, along with Radon and indoor dust, etc.
Fiberglass used for insulation is known to cause cancer, fibers are in Sheetrock and other items such as showers and sinks.
Plywood and cabinets are made with terrible chemicals that we should stay away from.
Kitchen sinks are one of the most dirty places. I do not know of a safe plumbing pipe to pass water through, perhaps if it were made out of wood, water itself is very contaminated, even after filtering.
Earthquakes are on the rise, most buildings will be unable to withstand the future, even if we are outside one might fall on us.
Practically all cleaning supplies, even many of the kinds thought of as natural, are unsafe.
Electricity presents many risks, not the least of which is Electromagnetic Fields.
Paints are generally made with many things that pose health risks.
Glass is another safety issue, even safety glass can cause a lot of harm, I call it witchcraft.
If we read the small print on products for buildings we will see that there are warnings telling us that practically all of them cause cancer and other problems.
There are so many toxic things it is not possible to give a complete list, I really do not know anything these days that is completely free from causing undue harm.
For all these reasons and more it is best just to remain homeless and not go into modern buildings more than we have to, I avoid them for days at a time and am glad.